DETECTION OF CD4+ T-LYMFOCYTE ADAPTIVE IMMUNITY CELL EXPRESSION IN MICE INFECTED WITH Salmonella typhimurium

Salmonella typhi is a gram-negative, intracellular facultative bacterium that can live and even reproduce in macrophages, resistant to lysosomal enzymes, which has the ability prevent phagosome-lysosome fusion, making it difficult kill. stimulates immune response host (Abbas et alll, 2016; Tores 2000). White turmeric (Curcuma zedoaria) one of herbal plants used as an immunomodulator. Immodulators white substances function increase phagocytosis macrophages destroy typhimurium bacteria. The purpose this study was determine difference between extract immunomodulator on number CD4+ T lymphocytes BALB/c mice infected with typhimurium. This research true experimental posttest only control group design. Mice were divided into 5 groups consisting negative group, positive test group. Analysis lymphocyte data showed significant p=0.013, indicated administration had effect